Polymeric trileaflet prosthetic heart valves: evolution and path to clinical reality
نویسندگان
چکیده
منابع مشابه
Polymeric trileaflet prosthetic heart valves: evolution and path to clinical reality.
Present prosthetic heart valves, while hemodynamically effective, remain limited by progressive structural deterioration of tissue valves or the burden of chronic anticoagulation for mechanical valves. An idealized valve prosthesis would eliminate these limitations. Polymeric heart valves (PHVs), fabricated from advanced polymeric materials, offer the potential of durability and hemocompatibili...
متن کاملToward optimization of a novel trileaflet polymeric prosthetic heart valve via device thrombogenicity emulation.
Aortic stenosis is the most prevalent and life-threatening form of valvular heart disease. It is primarily treated via open-heart surgical valve replacement with either a tissue or a mechanical prosthetic heart valve (PHV), each prone to degradation and thrombosis, respectively. Polymeric PHVs may be optimized to eliminate these complications, and they may be more suitable for the new transcath...
متن کاملIn vitro evaluation of a novel hemodynamically optimized trileaflet polymeric prosthetic heart valve.
Calcific aortic valve disease is the most common and life threatening form of valvular heart disease, characterized by stenosis and regurgitation, which is currently treated at the symptomatic end-stages via open-heart surgical replacement of the diseased valve with, typically, either a xenograft tissue valve or a pyrolytic carbon mechanical heart valve. These options offer the clinician a choi...
متن کاملProsthetic Aortic Heart Valves
In this review, the anatomy and structure of the aortic valve and its prostheses are comprehensively discussed. Cardiac anatomy and function, human heart valves and their prostheses are also extensively discussed. The current status of prosthetic heart valves along with the next generation of these devices is broadly deliberated. Ather promising options such astranscatheter technologies (percut...
متن کاملProsthetic heart valves.
The first prosthetic valve was implanted by Hufnagel in 1952 in a patient with aortic insufficiency. Since then, prosthetic valves have evolved into various mechanical and bioprosthetic shapes and sizes. Despite the excitement surrounding the current development of prosthetic heart valves, surgically implanted valves remain the mainstay of current practice, and this article discusses the hemody...
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ژورنال
عنوان ژورنال: Expert Review of Medical Devices
سال: 2012
ISSN: 1743-4440,1745-2422
DOI: 10.1586/erd.12.51